Platelet-rich plasma has been utilized for years in wound healing and orthopedic conditions, but more recently it has gained traction in aesthetic medicine, especially with respect to hair loss. Clinicians have had success in treating alopecia of various etiologies (lichen planopilaris, alopecia areata, etc.), but most of the limited data has been focused on PRP use for male and female-patern hair loss.
The mechanism of action involves platelets’ ability to aggregate together, activate, and release alpha-granules containing various growth factors, such as platelet derived growth factor, transforming growth factor, vascular endothelial growth factor, epidermal growth factor, fibroblast growth factor, and insulin like growth factor-1 (IGF-1). Their release increases angiogenesis and vascularization, providing resting telogen hairs the signal that they need to enter the anagen phase. This increased vascularization and mix of growth factors also fosters the proliferation of dermal papilla cells and inhibits apoptosis, helping to prolong the anagen phase. More specific to androgenetic alopecia, PRP may help to counteract certain effects of dihydrotestosterone (DHT).
Platelet-rich plasma is fully autologous and thus provides patients a more “natural” treatment, with side effects limited to procedural discomfort and bruising.
There is no standard system, quantity, or interval of treatment regarding PRP for hair loss, which is why we currently utilize a proprietary hyperconcentrated platelet rich plasma concentration and treat patients monthly 4 times, then reevaluate after 8 to 12 months. If a patient has a response, then retreatment at follow-up may result in continued efficacy if performed at a 6- to 12-month basis.
PRP Injections for the treatment of hair loss is not permanent . Upon completion of the initial treatment protocol of 4 treatments (1x per month), maintenance treatments will be required 3-4 times per year to maintain the results.
There is no standard reason for male and female-pattern hair loss. Meet with us so we can tailor your treatment designed specifically for you!